Did you mean tamatinib dabrafenib?
Displaying all 2 drugs
Dabrafenib
Dabrafenib mesylate (Tafinlar) is a reversible ATP-competitive kinase inhibitor and targets the MAPK pathway. It was approved on May 29, 2013, for the treatment of melanoma with V600E or V6000K mutation. It was also used for metastatic non-small cell lung cancer with the same mutation. In May 2018, Tafinlar (dabrafenib),...
Approved
Investigational
Matched Synonyms: … Dabrafenib …
Matched Name: … Dabrafenib …
Matched Description: … Dabrafenib mesylate (Tafinlar) is a reversible ATP-competitive kinase inhibitor and targets the MAPK ... [L41955] In May 2018, Tafinlar (dabrafenib), in combination with Mekinist ([DB08911]), was approved …
Matched Salts name: … Dabrafenib mesylate …
Matched Categories: … dabrafenib …
Matched Name: … Dabrafenib …
Matched Description: … Dabrafenib mesylate (Tafinlar) is a reversible ATP-competitive kinase inhibitor and targets the MAPK ... [L41955] In May 2018, Tafinlar (dabrafenib), in combination with Mekinist ([DB08911]), was approved …
Matched Salts name: … Dabrafenib mesylate …
Matched Categories: … dabrafenib …
Trametinib
Trametinib is an orally bioavailable mitogen-activated extracellular signal-regulated kinase 1 (MEK1) and MEK2 inhibitor.[A258298,A258293] It was first approved by the FDA in May 2013 for the treatment of melanoma. It was later approved by Health Canada on July 18, 2013 and by the European Commission on June 30, 2014. Trametinib...
Approved
Matched Synonyms: … Trametinib …
Matched Name: … Trametinib …
Matched Description: … non-small cell lung cancer and thyroid cancer, as monotherapy or in combination with [dabrafenib], a ... Trametinib is an orally bioavailable mitogen-activated extracellular signal-regulated kinase 1 (MEK1) ... [L45583] Trametinib is currently approved to treat a variety of cancers with BRAF mutations, such as …
Matched Salts name: … Trametinib dimethyl sulfoxide …
Matched Categories: … trametinib …
Matched Name: … Trametinib …
Matched Description: … non-small cell lung cancer and thyroid cancer, as monotherapy or in combination with [dabrafenib], a ... Trametinib is an orally bioavailable mitogen-activated extracellular signal-regulated kinase 1 (MEK1) ... [L45583] Trametinib is currently approved to treat a variety of cancers with BRAF mutations, such as …
Matched Salts name: … Trametinib dimethyl sulfoxide …
Matched Categories: … trametinib …
Displaying all 2 drugs